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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS20
All Species:
16.36
Human Site:
Y1237
Identified Species:
32.73
UniProt:
P59510
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59510
NP_079279.3
1910
214721
Y1237
R
Q
V
L
C
M
N
Y
H
Q
P
I
D
E
N
Chimpanzee
Pan troglodytes
XP_528704
1935
216502
Y1268
R
Q
V
M
C
V
N
Y
S
D
H
V
I
D
R
Rhesus Macaque
Macaca mulatta
NP_001104009
1911
214939
Y1238
R
Q
V
L
C
M
N
Y
H
Q
P
I
D
E
N
Dog
Lupus familis
XP_852138
2091
233309
Y1240
R
Q
V
L
C
I
N
Y
H
Q
P
I
N
E
N
Cat
Felis silvestris
Mouse
Mus musculus
P59511
1906
212023
Y1233
R
R
V
L
C
V
N
Y
H
Q
L
V
D
E
S
Rat
Rattus norvegicus
Q9WUQ1
967
105687
P319
I
Y
E
E
Q
K
G
P
E
V
T
S
N
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505519
1995
223408
N1302
L
V
I
C
Q
L
P
N
G
E
M
S
S
D
Q
Chicken
Gallus gallus
XP_416037
1725
194026
D1077
S
P
C
T
V
T
C
D
S
G
I
I
T
R
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663807
2516
282446
I440
S
K
C
S
R
K
Y
I
T
E
F
L
D
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395557
1763
199932
N1115
S
N
K
C
S
A
S
N
K
P
D
N
I
T
A
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
L1329
D
R
N
T
R
P
R
L
K
K
T
C
E
K
D
Sea Urchin
Strong. purpuratus
XP_791211
1693
190452
W1044
R
R
I
F
R
S
Q
W
R
T
G
A
W
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.3
94.1
69.1
N.A.
70.3
23.5
N.A.
57.2
57.1
N.A.
32.6
N.A.
N.A.
32
31.5
38.1
Protein Similarity:
100
67.6
96.9
78.3
N.A.
83.4
31.2
N.A.
70.7
71.7
N.A.
46.6
N.A.
N.A.
46.9
47
53.5
P-Site Identity:
100
40
100
86.6
N.A.
66.6
0
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
0
0
6.6
P-Site Similarity:
100
66.6
100
100
N.A.
93.3
6.6
N.A.
26.6
6.6
N.A.
26.6
N.A.
N.A.
6.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
9
0
9
17
% A
% Cys:
0
0
17
17
42
0
9
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
9
0
9
9
0
34
17
9
% D
% Glu:
0
0
9
9
0
0
0
0
9
17
0
0
9
34
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
9
9
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
34
0
9
0
0
0
0
% H
% Ile:
9
0
17
0
0
9
0
9
0
0
9
34
17
0
0
% I
% Lys:
0
9
9
0
0
17
0
0
17
9
0
0
0
9
0
% K
% Leu:
9
0
0
34
0
9
0
9
0
0
9
9
0
0
0
% L
% Met:
0
0
0
9
0
17
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
42
17
0
0
0
9
17
0
25
% N
% Pro:
0
9
0
0
0
9
9
9
0
9
25
0
0
0
9
% P
% Gln:
0
34
0
0
17
0
9
0
0
34
0
0
0
0
17
% Q
% Arg:
50
25
0
0
25
0
9
0
9
0
0
0
0
9
9
% R
% Ser:
25
0
0
9
9
9
9
0
17
0
0
17
9
0
9
% S
% Thr:
0
0
0
17
0
9
0
0
9
9
17
0
9
25
0
% T
% Val:
0
9
42
0
9
17
0
0
0
9
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% W
% Tyr:
0
9
0
0
0
0
9
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _